Name : Asst. Prof. Dr. Juthamas Ratanavaraporn (ผศ.ดร.จุฑามาศ รัตนวราภรณ์)
Position : Assistant Professor
Research Topics : Biomaterial technology , Tissue engineering technology, Drug delivery system
Contact address : Building 1, 2nd Floor, Room 203, Faculty of Engineering, Chulalongkorn University
Email : juthamas.r@chula.ac.th
Phone : +66 (02) 218-6793
PhoneExtension : ext. 15
Education
Ph.D. (Chemical Engineering), Chulalongkorn University (2009)
M.Eng. (Chemical Engineering), Chulalongkorn University (2006)
B.Eng. (Chemical Engineering), Chulalongkorn University (2004)
Academic Awards
Awards
Japan Society for the Promotion of Science (JSPS) scholarship

Publications
1. Piyarat Sungkhaphan, Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Development of Thai silk fibroin/hyaluronic acid microspheres and the application on controlled release of curcumin, Engineering Journal, Vol. 21, pp 139-153, 2017
2. Juthamas Ratanavaraporn, Kumpanart Soontornvipart, Somruetai Shuangshoti, Shanop Shuangshoti, Siriporn Damrongsakkul, Localized delivery of curcumin from injectable gelatin/Thai silk fibroin microspheres for anti-inflammatory treatment of osteoarthritis in a rat model, Inflammopharmacol, Vol. 25, pp. 211–221, 2017 (Impact factor-2016 = 2.304)
3. Kantarat Lerdchai, Jutarat Kitsongsermthon, Juthamas Ratanavaraporn, Sorada Kanokpanont, Siriporn Damrongsakkul, Thai silk fibroin/gelatin sponges for the dual controlled release of
curcumin and docosahexaenoic acid for anticancer treatment, Journal of Pharmaceutical Sciences, Vol. 105, pp. 221-230, 2016 (Impact factor-2014 = 2.59).
4. Chotika Dararutana, Juthamas Ratanavaraporn, Sittisak Honsawek, Sorada Kanokpanont, Siriporn Damrongsakkul, Characteristics and osteoconductivity of bone composite scaffolds made of thai silk fibroin, gelatin and inorganic compounds: a comparative study of β-tricalcium phosphate and hydroxyapatite, Macromolecular Symposia, Vol. 354, pp. 258–264, 2015.
5. Vítor E Santo, Juthamas Ratanavaraporn, Keisuke Sato, Manuela E Gomes, João F Mano, Rui L Reis, Yasuhiko Tabata, Cell engineering by the internalization of bioinstructive micelles for enhanced bone regeneration, Nanomedicine (Lond.), Vol. 10, pp. 1707–1721, 2015 (Impact factor-2014 = 5.413)
6. Pornanong Aramwit, Nungruthai Jaichawa, Juthamas Ratanavaraporn, Teerapol Srichana, A comparative study of type A and type B gelatin nanoparticles as the controlled release carriers for different model compounds, Materials Express, Vol. 5, pp 241-248, 2015 (Impact factor-2014 = 2.299)
7. Pornanong Aramwit, Juthamas Ratanavaraporn, Sanong Ekgasit, Duangta Tongsakul, Nipaporn Bang, A green salt-leaching technique to produce sericin/PVA/glycerin scaffolds with distinguished characteristics for wound-dressing applications, Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 103(4), pp. 915-924, 2015 (Impact factor-2014 = 2.759)
8. Pornanong Aramwit, Nipaporn Bang, Juthamas Ratanavaraporn, Titpawan Nakpheng, Teerapol Srichana, An anti-cancer cordycepin produced by Cordyceps militaris growing on the dead larva of Bombyx Mori silkworm, Journal of Agricultural Science, Vol. 6, pp 41-53, 2014 (Impact factor-2013 = 2.891)
9. Pornanong Aramwit, Juthamas Ratanavaraporn, Tippawan Siritientong, Improvement of physical and wound adhesion properties of silk sericin and polyvinyl alcohol (PVA) dressing using glycerin, Advances in Skin & Wound Care, Vol. 28, pp 358-367, 2015.
10. Juthamas Ratanavaraporn, Sorada Kanokpanont, Siriporn Damrongsakkul, The development of injectable gelatin/silk fibroin microspheres for the dual delivery of curcumin and piperine, Journal of Materials Science: Materials in Medicine, Vol. 25, pp 401–410, 2014 (Impact factor-2013 = 2.325)
11. Pornanong Aramwit, Nipaporn Bang, Juthamas Ratanavaraporn, Sanong Ekgasit, Green synthesis of silk sericin-capped silver nanoparticles and their potent anti-bacterial activity, Nanoscale Research Letters, Vol. 9, pp 79, 2014 (Impact factor-2013 = 2.52)
12. Peepattra Wantanasiri, Juthamas Ratanavaraporn, Rungnapha Yamdech, Pornanong Aramwit, Fabrication of silk sericin/alginate microparticles by electrohydrodynamic spraying technique for the controlled release of silk sericin, Journal of Electrostatics,Vol.72, pp 22–27, 2014 (Impact factor-2013 = 1.000)
13. Tippawan Siritientong, Juthamas Ratanavaraporn, Teerapol Srichana, Pornanong Aramwit, Preliminary characterization of genipin-crosslinked silk sericin/poly(vinyl alcohol) films as two-dimensional wound dressings for the healing of superficial wounds, BioMed Research International, Vol.2013, Article ID 904314, 2013 (Impact factor-2013 = 2.880)
14. Tippawan siritientong, Apichai angspatt, Juthamas Ratanavaraporn, Pornanong Aramwit, Clinical potential of a silk sericin-releasing bioactive wound dressing for the treatment of split-thickness skin graft donor sites, Pharmaceutical Research, Vol. 31, pp 104-113, 2014 (Impact factor-2012 = 4.742)
15. Siraporn Somvipart, Sorada Kanokpanont, Rattapol Rangkupan, Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Development of electrospun beaded fibers from Thai silk fibroin and gelatin for controlled release application, International Journal of Biological Macromolecules, Vol. 55, pp 176– 184, 2013 (Impact factor-2012 = 2.596)
16. Rungnapa Vorrapakdee, Sorada Kanokpanont, Juthamas Ratanavaraporn, Saranatra Waikakul, Chris Charoenlap, Siriporn Damrongsakkul, Modification of human cancellous bone using Thai silk fibroin and gelatin for enhanced osteoconductive potential, Journal of Materials Science: Materials in Medicine, Vol. 24, pp 735–744, 2013 (Impact factor-2012 = 2.141)
17. Sorada Kanokpanont, Siriporn Damrongsakkul, Juthamas Ratanavaraporn, Pornanong Aramwit, Physico-chemical properties and efficacy of silk fibroin fabric coated with different waxes as wound dressing, International Journal of Biological Macromolecules, Vol. 55, pp 88– 97, 2013 (Impact factor-2012 = 2.596)
18. Pornanong Aramwit, Tippawan Siritienthong, Teerapol Srichana, Juthamas Ratanavaraporn, Accelerated healing of full-thickness wounds by genipin-crosslinked silk sericin/PVA scaffolds, Cells Tissues Organs, Vol. 197, pp 224–238, 2013 (Impact factor-2012 = 2.2)
19. Tippawan Siritienthong, Juthamas Ratanavaraporn, Pornanong Aramwit, Development of ethyl alcohol-precipitated silk sericin/polyvinyl alcohol scaffolds for accelerated healing of full-thickness wounds, International Journal of Pharmaceutics, Vol. 439, pp 175-86, 2012 (Impact factor-2012 = 3.458)
20. Tanom Wongputtaraksa, Juthamas Ratanavaraporn, Rath Pichyangkura, Siriporn Damrongsakkul, Surface modification of Thai silk fibroin scaffolds with gelatin and chitooligosaccharide for enhanced osteogenic differentiation of bone marrow-derived mesenchymal stem cells, Journal of Biomedical Materials Research Part B Applied Biomaterials, Vol. 100, pp 2307-2315, 2012 (Impact factor-2012 = 2.308)
21. Sorada Kanokpanont, Siriporn Damrongsakkul, Juthamas Ratanavaraporn, Pornanong Aramwit, An innovative bi-layered wound dressing made of silk and gelatin for accelerated wound healing, International Journal of Pharmaceutics, Vol. 436, pp 141– 153, 2012 (Impact factor-2012 = 3.458)
22. Juthamas Ratanavaraporn, Hiroyuki Furuya, Yasuhiko Tabata, Local suppression of pro-inflammatory cytokines and the effects in BMP-2-induced bone regeneration, Biomaterials, Vol. 33, pp. 304-316, 2012 (Impact factor-2011 = 7.882)
23. Juthamas Ratanavaraporn and Yasuhiko Tabata, Enhanced osteogenesis of bone 1 morphogenetic protein-2 by 2-O-desulfated heparin, Acta Biomaterialia, Vol. 8, pp. 173–182, 2012 (Impact factor-2011 = 4.822)
24. Juthamas Ratanavaraporn, Hiroyuki Furuya, Hiroshi Kohara, Yasuhiko Tabata, Synergistic effects of the dual release of stromal cell-derived factor-1 and bone morphogenetic protein-2 from hydrogels on bone regeneration, Biomaterials, Vol. 32, pp. 2797-2811, 2011 (Impact factor-2010 = 7.365)
25. Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Sorada Kanokpanont, Masaya Yamamoto, Yasuhiko Tabata, Osteogenic differentiation of bone-marrow-derived stem cells cultured with mixed gelatin and chitooligosaccharide scaffolds, Journal of Biomaterials Science, Polymer Edition, Vol. 22, pp. 1083–1098, 2011 (Impact factor-2009 = 2.505)
26. Juthamas Ratanavaraporn, Ratthapol Rangkupan, Hathairat Jeeratawatchai, Sorada Kanokpanont, Siriporn Damrongsakkul, Influences of physical and chemical crosslinking techniques on electrospun type A and B gelatin fiber mats, International Journal of Biological Macromolecules, Vol. 47, pp. 431–438, 2010 (Impact factor-2010 = 2.366)
27. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Modulation of in vitro attachment, proliferation and osteogenic differentiation of rat bone marrow-derived stem cells using different molecular weight chitosans and their blends with gelatin, Journal of Biomaterials Science, Polymer Edition, Vol. 21, pp. 979–996, 2010 (Impact factor-2008 = 2.158)
28. Nuttapon Vachiraroj, Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Rath Pichyangkura, Tanom Banaprasert, Sorada Kanokpanont, A comparison of Thai silk fibroin-based and chitosan-based materials on in vitro biocompatibility for bone substitutes, International Journal of Biological Macromolecules, Vol. 45, pp. 470–477, 2009 (Impact factor-2008 = 1.867)
29. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Growth and osteogenic differentiation of adipose-derived and bone marrow-derived stem cells on chitosan and chitooligosaccharide films, Carbohydrate Polymers, Vol. 78, pp. 873-878, 2009 (Impact factor-2008 = 2.644)
30. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Effects of acid types on physical and biological properties of collagen scaffolds, Journal of Biomaterials Science, Polymer Edition, Vol. 19, No. 7, pp. 945-952, 2008 (Impact factor-2008 = 2.158)
31. Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Neeracha Sanchavanakit, Tanom Banaprasert, Sorada Kanokpanont, Comparison of gelatin and collagen scaffolds for fibroblast cell culture, Journal of Metals, Materials and Minerals, Vol. 16, No. 1, pp 31-36, 2006

Proceedings and International Conferences
1. Wanwarang Wannaborvorn, Anita Manassakorn, Siriporn Damrongsakkul, Juthamas Ratanavaraporn, A comparative study on glutaraldehyde crosslinking methods of three-dimensional Thai silk fibroin/gelatin scaffolds for medical application, Pure and Applied Chemistry International Conference 2018 (PACCON 2018), International Convention Center, Hat Yai, Songkhla, Thailand, February 7-9, 2018
2. Patchara Umprasert, Siriporn Damrongsakkul, Juthamas Ratanavaraporn, Effects of silver sulfadiazine on crosslinking and properties of Thai silk fibroin/gelatin films, Pure and Applied Chemistry International Conference 2018 (PACCON 2018), International Convention Center, Hat Yai, Songkhla, Thailand, February 7-9, 2018
3. Juthamas Ratanavaraporn, Papawee Likitdecharoj, Development of gelatin derivative microsphere for delivery of green tea extract for the treatment of osteoarthritis, Tissue Engineering and Regenerative Medicine International Society- European Chapter Meeting (TERMIS-EU 2017), Davos, Switzerland, June 26 - 30, 2017,
4. Nattakan Chantong, Siriporn Damrongsakkul, Suthiluk Patumraj, Juthamas Ratanavaraporn, Effect of anionic surfactants on the gelation of silk fibroin and solubility of curcumin for controlled release application, The 5th Asia-Pacific Congress of Sericulture and Insect Biotechnology 2017, Maruay Gerdan Hotel, Bangkok, Thailand, Feb 28-March 2, 2017
5. Juthamas Ratanavaraporn, Kumpanart Soontornvipart, Somruetai Shuangshoti, Shanop Shuangshoti, Siriporn Damrongsakkul, Localized and controlled delivery of curcumin from injectable gelatin/Thai silk fibroin microspheres for the treatment of osteoarthritis in a rat model. Tissue Engineering and Regenerative Medicine International Society- Asia Pacific Meeting (TERMIS-AP 2016), Fullon Hotel Tamsui Fishermen’s Wharf, Taipei, Taiwan, September 3-6, 2016
6. Patcharida Kongton, Juthamas Ratanavaraporn, Jutarat Kitsongsermthon, Siriporn Damrongsakkul, Physical characteristics and curcumin entrapment efficiency of gelatin/Thai silk fibroin microspheres, The 2016 Biomedical Engineering International Conference (BMEiCON-2016), Laung Prabang View Hotel, Laung Prabang, Laos, December 7-9, 2016
7. Papawee Likitdecharoj, Juthamas Ratanavaraporn, Preparation and characterization of anionized and cationized gelatin derivatives and their microspheres for drug delivery system, The 2016 Biomedical Engineering International Conference (BMEiCON-2016), Laung Prabang View Hotel, Laung Prabang, Laos, December 7-9, 2016
8. Juthamas Ratanavaraporn, Papawee Likitdecharoj, Kanyaluk Kaewprasit, Siriporn Damrongsakkul, Various gelatin derivative carriers for the controlled release of natural-derived molecules for regenerative medicine applications, World Conference on Regenerative Medicine (WCRM2015), Congress Center Leipzig, Leipzig, Germany, October 21–23, 2015.
9. Kantarat Lerdchai, Juthamas Ratanavaraporn, Sorada Kanokpanont, Siriporn Damrongsakkul, The dual release of curcumin and docosahexaenoic acid from Thai silk fibroin/gelatin hydrogels for the anti-proliferation of cancer cells, Tissue Engineering and Regenerative Medicine International Society-Asia Pacific Meeting (TERMIS-AP 2014), Exco, Daegu, Republic of Korea, September 24-27, 2014
10. Chotika Dararutana, Juthamas Ratanavaraporn, Sittisak Honsawek, Sorada Kanokpanont, Siriporn Damrongsakkul, Characteristics and osteoconductivity of bone composite scaffolds made of Thai silk fibroin, gelatin and inorganic compounds: a comparative study of β-tricalcium phosphate and hydroxyapatite, The IUPAC World Polymer Congress (MACRO2014), Chiangmai International Convention and Exhibition Center, Chiangmai, Thailand, July 6-11, 2014
11. Juthamas Ratanavaraporn, Sorada Kanokpanont, Siriporn Damrongsakkul, Development of gelatin/silk fibroin microspheres for dual releases of curcumin and piperine, Asia Pacific Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AP)-2013, Shanghai and Wuzhen, China, October 23-26, 2013
12. Siriporn Damrongsakkul, Sorada Kanokpanont, Juthamas Ratanavaraporn, Thai silk fibroin/gelatin system for tissue engineering and controlled release applications, The 62nd SPSJ Symposium on Macromolecules, Kanazawa, Japan, September 11, 2013
13. Santo VE , Sato K, Juthamas Ratanavaraporn, Gomes ME, Mano JF, Reis RL and Tabata Y, Intracellular delivery of dexamethasone as key supplement for new orthotopic bone formation , proceeding in Fall Symposium of International Society for Biomaterials, New Orleans, United States of America, October 2012
14. Juthamas Ratanavaraporn, Nipaporn Bang, Pornanong Aramwit, Anti-Cancer Activity of Cordycepin Produced from the Dead Body of Bombyx Mori, proceeding in Second International Meeting on Organic Materials for a Better Future (FUTURMAT2), Conference Centre Riva Marina Resort, Brindisi, Italy, September 16-20 2012 (Poster presentation)
15. Santo VE , Sato K, Ratanavaraporn J, Gomes ME, Mano JF, Reis RL and Tabata Y, Enhanced orthotopic bone regeneration promoted by intracellular delivery of dexamethasone, proceeding in the 3rd TERMIS World Congress 2012, Vienna, Austria, September 2012
16. Santo VE , Sato K, Ratanavaraporn J, Gomes ME, Mano JF, Reis RL and Tabata Y, Enhanced in vitro and in vivo osteogenesis of rat bone marrow stem cells through intracellular delivery of dexamethasone with gelatin micelles, proceeding in XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs (IFAO 2011), Porto, Portugal, October 2011
17. Juthamas Ratanavaraporn and Yasuhiko Tabata, Modulation of inflammation to enhance bone regeneration by dual delivery of anti-IL-6 drug and bone morphogenetic protein-2 with gelatin hydrogels, proceeding in Tissue Engineering and Regenerative Medicine International Society, European (TERMIS EU 2011), Palacio de Congresos de Granada, Granada, Spain, June 7-10, 2011 (Poster presentation)
18. Juthamas Ratanavaraporn, Hiroyuki Furuya, Yasuhiko Tabata, Synergistic effect of stromal cell-derived factor-1 and bone morphogenetic protein-2 released from gelatin hydrogels for in vivo bone regeneration, proceeding in International Bone-Tissue-Engineering Congress (Bone-tec 2010), Exhibition Ground, Hannover, Germany, October 7-10, 2010 (Poster presentation)
19. Juthamas Ratanavaraporn, Yasuhiko Tabata, The combination of stromal cell-derived factor-1 and bone morphogenetic protein-2 for bone tissue engineering, proceeding in Tissue Engineering and Regenerative Medicine International Society,Asia Pacific (TERMIS AP 2010), Sheraton on the Park, Sydney, Australia, September 15-17, 2010 (Oral presentation)
20. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Mesenchymal stem cells from adipose tissue and bone marrow: A comparative study on chitosan, proceeding in the 22th European Conference on Biomaterials: The Annual Conference of the European Society for Biomaterials (ESB 2009), Beaulieu Convention Centre, Lausanne, Switzerland, September 7-11, 2009 (Poster presentation)
21. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Response of bone marrow-derived stem cells (MSCs) on gelatin/chitosan and gelatin/ chitooligosaccharide films, proceeding in the 13th International Conference on BioMedical Engineering 2008 (ICBME 2008), Suntec International Convention & Exhibition Centre,
Singapore, December 3-6, 2008 (Oral presentation)
22. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Osteogenic differentiation of rat mesenchymal stem cells (MSCs) on gelatin/chitosan scaffolds: A preliminary study, proceeding in the 1st Thailand International Conference on Oral Biology: Biology of Mineralized Tissue (TICOB 2008), Faculty of Chulalongkorn University, Bangkok, Thailand, May 7, 2008 (Poster presentation)
23. Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Neeracha Sanchavanakit, Tanom Banaprasert, Yasuhiko Tabata, Sorada Kanokpanont, Comparison of gelatin, collagen/gelatin and collagen scaffolds for dermal regeneration, proceeding in the 6th Asian BioCeramics Symposium 2006 (ABC2006), The Sofitel Central Plaza, Bangkok, Thailand, November 7-
10, 2006 (Oral presentation)
24. Juthamas Ratanavaraporn, Siriporn Damrongsakkul, Sorada Kanokpanont, Morphology and properties of collagen/gelatin scaffolds, proceeding in the Thai Society for Biotechnology Annual Meeting at BioThailand 2005, the Queen Sirikit National Convention Center, Bangkok, Thailand, November 2-5, 2005 (Poster presentation)
25. Juthamas Ratanavaraporn and Yasuhiko Tabata, Modulation of inflammation by delivery of anti-IL-6 drug and bone morphogenetic protein-2 for enhanced bone regeneration, proceeding in 33th Congress of Japan Society for Biomaterials, Kyoto, Japan, November 21-22, 2011 (Poster presentation)
26. Juthamas Ratanavaraporn, Hiroyuki Furuya, Hiroshi Kohara, Yasuhiko Tabata, Enhanced bone formation by a dual release of stromal cell-derived factor-1 and bone morphogenetic protein-2 from gelatin hydrogels, proceeding in BMP meeting, Osaka, Japan, July 31, 2011 (Oral presentation)
27. Juthamas Ratanavaraporn and Yasuhiko Tabata, Enhanced bone formation by the dual release of SDF-1/BMP-2, proceeding in The Japanese Society for Regenerative Medicine (JSRM2011), Keio Plaza Hotel, Tokyo, Japan, March 1-2, 2011 (Poster presentation)
28. Juthamas Ratanavaraporn and Yasuhiko Tabata, Enhanced bioactivity and osteoinductivity of bone morphogenetic protein-2 in mesenchymal stem cells by 2-O desulfated heparin, proceeding in Japanese Society for Biomaterials (JSB2010), Grand Prince Hotel, Hiroshima, Japan, November 29-30, 2010 (Poster presentation)
29. Juthamas Ratanavaraporn, Sorada Kanokpanont, Yasuhiko Tabata, Siriporn Damrongsakkul, Effects of acid types on properties of collagen solutions and collagen scaffolds: A preliminary study, proceeding in the 5th National Conference on Biomedical Engineering, (NCBME 2007), The Twin Tower Hotel, Bangkok, Thailand, July 8, 2007 (Poster presentation)
30. Juthamas Ratanavaraporn, Sorada Kanokpanont, Rath Pichyangkura, Siriporn Damrongsakkul, Response of mesenchymal stem cells on chitosans with various molecular weights, proceeding in the 5th National Conference on Biomedical Engineering, (NCBME 2007), The Twin Tower Hotel, Bangkok, Thailand, July 8, 2007 (Poster presentation)
Research Areas
- Biomaterial technology : fabrication, modification, and characterization of material
- Tissue engineering technology : scaffolding and cells/stem cell technology for dermal, adipose, bone, and osteochondral tissue regeneration
- Drug delivery system : development of drug-controlled release carrier for treatment of cancer, osteoarthritis, and diabetic diseases
Research Interests
Biomaterial technology , Tissue engineering technology, Drug delivery system